SHE level 11 SCQF credit points 15 ECTS credit points 7.5 Module code MMB130821 Module Leader Catherine Wright School School of Health and Life Sciences Subject Biological and Biomedical Sciences Trimester A (September start)
Summary of content This module will extend the student's knowledge of normal physiology relevant to all types of diabetes. This module will provide an in-depth knowledge and understanding of the macrovascular complications and selected microvascular complications of this disease along with the scientific basis for diagnosis, the genetic basis of the disease, acute diabetic emergencies and the pharmacological and non-pharmacological management of diabetes. Chronic complications of diabetes will be critically evaluated, in particular eye disease, wound healing, infection and depression. Treatment and support for these complications will be discussed.
Module details Syllabus arrow_forward Macrovascular complications: Mechanisms of vascular damage, hypertension, myocardial infarct mechanisms and therapeutics. Stroke - types and treatments and functional consequences. Peripheral vascular disease; consequences and therapies. Microvascular complications: Polyol pathways and advanced glycosylation end products. Neuropathy; autonomic, sensory and motor. Existing and future therapies. Neuropathic pain. Pathophysiology and therapeutics. Nephropathy, hyperfiltration, reduced GFR, end-stage renal failure. Detection of microalbuminurea, proteinurea albumin/creatinine ratio. Relationship between nephropathy and cardiovascular pathologies. Drug treatment of nephropathy. Dialysis. Skin and wound healing in the diabetic patient: Causes and complications of wound healing failure in people with diabetes. Traditional wound management (dressings) and novel experimental methods of improving wound healing. Patient support. Emerging and novel therapies for diabetes: Introduction to current replacement therapies for B-cell function and the potential of stem cell technologies, allo-transplantation and personalised medicine as future benefits for diabetic patients Gastrointestinal complications of diabetes include gastro-oesophageal reflux disease, gastroparesis, intestinal enteropathy and non-alcoholic fatty liver disease. Chronic complications of the liver. Diagnosis and medication. Eye diseases associated with diabetes: Retinopathy, cataract, anterior segment of the eye. Risk factors, symptoms, clinical signs, treatment. Mental health issues: Depression and anxiety; clinical diagnosis, diabetes-specific problems, patient management (lifestyle factors) and therapies available. Symptoms and consequences of depression for the diabetic patient. Neurobiology of depression; reason for increased incidence with diabetes and how these co-morbidities are best managed. An understanding of the mechanisms of action and side-effects of anti-depressant drugs. Infection and the diabet
Learning outcomes arrow_forward On successful completion of the module the students should be able to: 1. Understand and assess the mechanisms of cardiovascular, nerve and renal damage in diabetes; appreciating and critically evaluating pharmacological strategies related to these systems. 2. Have in depth knowledge of the principles and practices of existing and novel technologies to treat Diabetes in individuals and to deal with organs affected by chronic complications 3. Critically analyse the pathologic mechanisms and therapeutic support for hepatic and gastrointestinal tract complications; and the overarching risk factors, symptoms, clinical signs and treatment of eye disease associated with diabetes. 4. Have extensive knowledge of specific infections associated with this patient group; and the principles and practices of wound management. 5. Have knowledge of the clinical diagnosis, management and therapies associated with depression and other mental health problems related to diabetes.
Teaching / learning strategy arrow_forward A blended learning approach will be used in this module, utilising a wide range of teaching methods including lectures, tutorials and revision sessions. Lecture material will introduce the key theoretical concepts and principles, with the GCU virtual learning environment used to encourage student engagement through additional reading with materials provided by module tutors including web-links, supplementary videos and published scientific articles and reviews. The VLE will also be used to provide quizzes and other revision aids. Students will be encouraged to critically interpret data reported in scientific publications. Formative feedback will be given during the module, within 3 weeks of submission. Module tutors also offer face-face feedback regarding assessment if requested.
Indicative reading arrow_forward Transferrable skills arrow_forward The student's personal transferable skills should be extended in the following areas: - Critical thinking and problem solving - Communication (oral and written) - Information retrieval from library and electronic sources - Review and critical analysis of published data - Independent study skills
Module structure Activity Total hours Lectures 24 Tutorials 12 Practicals 0 Seminars 0 Independent Learning 96 Assessment 18 Placement 0
Assessment methods Component Duration Weighting Threshold Description Course Work001 100 45 CW1: Short essay questions