SHE Level 5
SCQF Credit Points 15.00
ECTS Credit Points 7.50
Module Code MMB725785
Module Leader Christopher Borge
School School of Health and Life Sciences
Subject Nursing
  • A (September start)
  • B (January start)

Pre-Requisite Knowledge

Experience and knowledge of human physiology.

Summary of Content

This module will extend the underpinning pathophysiological knowledge required by individuals wishing to advance their practice. It adopts a systems approach utilising: 1. General physiological principles 2. The physiology and pathophysiology of selected body systems including those of direct relevance to the student's sphere of practice 3. Current approaches to treatment of important pathophysiological conditions, e.g. cardiac failure, diabetes 4. Discussion of treatment options including those currently under development.


Current issues in applied pathophysiology and therapeutics in the following areas: Cell structure and function; neoplasia; current approaches to treatment of malignant disorders Homeostasis in health and disease Cardiovascular system; myocardial infarction; cardiac failure; current approaches to treatment Diabetes Nervous system; vascular problems; problems caused by trauma; dementia; depression; current approaches to treatment. Renal system; acute kidney injury; chronic renal dysfunction; current approaches to treatment. Respiratory system; asthma; chronic obstructive pulmonary disorders Pathophysiology of ageing, impact of comorbidities and complexity of management due to advanced age and/or frailty. There may also be scope to include student requests based on their clinical interests.

Learning Outcomes

On successful completion of this module students should be able to:1. Demonstrate evidence of advanced professional knowledge and understanding of the principles of homeostatic mechanisms, normal functioning, and physiology. 2. Demonstrate advanced knowledge of pathophysiology of selected human body systems. 3. Discuss clinical interventions that could be used to address signs and symptoms identified by the assessment of patients or clients within their own area of practice.4. Analyse their own and others' practice in relation to contemporary therapeutic approaches.

Teaching / Learning Strategy

The module will be delivered using a blended approach including online via GCULearn with a variety of resources, & face-to-face in a classroom setting. The main activities to be carried out by students are directed and independent study to develop knowledge and skills relating to the module syllabus. The teaching and learning strategies to be employed include lectures/video lectures, podcasts, narrated presentations, seminars/online a/synchronous discussion and tutorials/online self-directed study to engage the students in the key concepts which will then be developed through guided activities and directed learning.

Indicative Reading

BRASHERS, V.L. (2006) Clinical applications of pathophysiology. An evidence-based approach. (3rd edition). USA: Elsevier. COURNEYA, C. A, and PARKER, M.J. (2011) Cardiovascular physiology. A clinical approach. London: Wolters Kluwer/Lippincott Williams and Wilkins. GROSSMAN, S.C. and PORTH, C.M. (2014) Porth's pathophysiology. Concepts of altered health states . (9th edition) London: Wolters Kluwer/Lippincott Williams and Wilkins. McCANCE, K.L. and HUETHER, S.E. (Editors) (2014) Pathophysiology. The biologic basis for disease in adults and children. (7th edition) USA: Elsevier. NAIR, M. and PEATE, I. (2013) Applied Pathophysiology . (3 rd Edition). Sussex: Wiley-Blackwell. RHODES, R.A. and BELL, D.R. (2012) Medical physiology. Principles for clinical medicine. (4 th edition). London: Wolters Kluwer/Lippincott Williams and Wilkins. URLs <> <> <> <> <> <>

Transferrable Skills

1. Working in a self-directed manner and taking responsibility for own learning, personal development and practice competence. 2. Develop communication and IT skills to underpin effective learning. 3. Communicate effectively in both written and oral forms. 4. Work effectively with others. 5. Underpin professional development by integration of theory and practice.

Module Structure

Activity Total Hours
Assessment (FT) 14.00
Independent Learning (FT) 100.00
Lectures (FT) 24.00
Tutorials (FT) 12.00

Assessment Methods

Component Duration Weighting Threshold Description
Exam (Dept) 01 2.00 100.00 50% Class testThe pass mark for this exam is 70%, the mark willthen be normalised in accordance with theUniversity's assessment regulations.Exceptions Case Number: 139