TRANSLATIONAL MEDICAL SCIENCE

SHE Level 5
SCQF Credit Points 15.00
ECTS Credit Points 7.50
Module Code MMB226358
Module Leader Yvonne Dempsie
School School of Health and Life Sciences
Subject Biological and Biomedical Sciences
Trimester
  • B (January start)

Pre-Requisite Knowledge

At least a 2:2 honours degree (or equivalent) in a biomedical or biological science discipline.

Summary of Content

This module will explore the development and structure of biomedical research. Students will be given various topics to choose from and asked to write a grant proposal. Grant proposals will be supervised by individual members of staff. Ethics and regulation around the use of both animal models of disease and regenerative medicine will be studied. Tutorials on writing a grant application will be given and will explore topics such as experimental methods and impact statements.

Syllabus

Regenerative medicine: Origins of stem cells and principles of stem cell technologies in tissue engineering and regenerative medicine. Ethical considerations. Animal models of disease: Use of animals in translational medicine. Genetic modification of animals. Ethics of animal research: The principles of reduction, refinement and replacement in the use of animals in research. Outline of the UK regulatory system for control of animal experimentation. Drug development: Research strategies to find new drugs for the treatment of diseases. Examples of drug development from pre-clinical stage to clinical trials. Grant writing: Effective scientific writing, development of research questions/hypotheses, ethical considerations.

Learning Outcomes

On successful completion of the module the student should be able to:1. Discuss ethical issues and regulation of biomedical research techniques.2. Critically interpret data from original research articles.3. Demonstrate a critical understanding of the principal theories, concepts and principles of biomedical research.

Teaching / Learning Strategy

This module is predominantly student centred learning, with guidance from specific supervisors with regards to subject material. Support tutorials will be given to aid consolidation of material and will include the use of interactive techniques, small group discussion and problem solving. Topics will be evidence-based and thus develop the student's ability to critically analyse new ideas.. This will aid broad and deeper learning and promote long-term retention of knowledge. Students will be exposed to real world problem solving in the context of biomedical research and the challenges that this creates. This module will provide students with key knowledge of experimental systems that are important to the advancement of medical bioscience research along with the ability to structure this information in an appropriate format. These knowledge and skills are sought after by both academia and industry thus are highly relevant to student employability.

Indicative Reading

Due to the nature of this module, most reading material is in the form of review or primary articles. These will regularly change to reflect the most up to date discoveries. Therefore, details of reading material will be given to students during the lectures.

Transferrable Skills

Through interactive tutorials students will develop transferrable skills including interpretation and critical analysis of scientific data, communication, problem solving and grant writing.

Module Structure

Activity Total Hours
Independent Learning (FT) 140.00
Tutorials (FT) 10.00

Assessment Methods

Component Duration Weighting Threshold Description
Course Work 01 n/a 100.00 50% Grant Application