SHE Level 4
SCQF Credit Points 30.00
ECTS Credit Points 15.00
Module Code MHB123734
Module Leader James Reilly
School School of Health and Life Sciences
Subject Biological and Biomedical Sciences
  • A (September start)-B (January start)

Pre-Requisite Knowledge

Successful completion of Neurophysiology 1 and 2

Summary of Content

The module will extend the student's knowledge of applied neuroanatomy, including the structure and function of the cerebellum and sub-cortical structures such as the basal ganglia and associated pathways. Embryological development of the CNS will be considered. Detailed upper limb anatomy will allow better understanding of the techniques used to evaluate peripheral nerve conditions. Physiology of visual and auditory sensory systems will provide basis for understanding sensory recording tests. Special topics will consider physiology and pathophysiology of the cardiovascular and respiratory systems.


Neuroanatomy & Neurophysiology Embryology: neural tube, origin of neurones and glia, neural crest, cell migration, formation of the brain and cord, myelination. Functions of subcortical structures and pathways: pyramidal and extrapyramidal systems, cerebellum and related pathways, alterations in muscle power and tone, disorders of movement (ataxia, ridgidity, chorea, athetosis, myoclonus). Fundamentals of visual and auditory systems. Peripheral Investigations EP & NCS: recording parameters, normal & abnormal waveforms. Nerve conduction studies: Detailed anatomy of the hand and lower arm in context; neuropathies, entrapments, traumatic neuropathy, myopathies, denervation, renervation, disorders of NMJ Other electrophysiological investigations, e.g. visual and auditory electrophysiological tests such as ERG, ABR, etc. For special topics, students can choose to study 2 from the following list: Unit 1: Psychopharmacology Unit 2: Neuropathophysiology and therapeutics Unit 3: System Pathophysiology and Pharmacology 1 - Cardiovascular system Unit 4: System Pathophysiology and Pharmacology 2 - Respiratory and GI systems Unit 5: System Pathophysiology and Pharmacology 3 - Pulmonary system

Learning Outcomes

On successful completion of this module, the student should be able to:1. Demonstrate a detailed understanding of the relationship between the dysfunction of subcortical structures and neurological symptomology.2. Describe upper limb anatomy relevant to peripheral nerve disorders.3. Explain the physiological processes involved in visual and auditory sensory processing.4. Critically evaluate instrumentation factors in sensory and peripheral recordings.5. Discuss the pathophysiological mechanisms underlying common conditions.6. Apply pharmacological knowledge to pathophysiological processes.

Teaching / Learning Strategy

Although delivered in year 3 this module is set and assessed at level 4 as the syllabus is continuous with Neurophysiology 4 with special topics; students are working towards final qualification as a Clinical Physiology Practitioners This specialist content of this module will be delivered mainly by senior NHS practitioners, clinicians and consultants. The main mode of delivery will be lectures supplemented by on-line exercises, guided reading and tutorial discussions of case study scenarios. Special topics will be delivered by research active GCU staff

Indicative Reading

Suggested Reading: Brodal, P. (2010) The Central Nervous System . 4 th Edition. Oxford. Naish, J. et al . (2011) Medical Sciences . Saunders. Michael-Titus, A. et al . (2010) The Nervous System: Basic Science and Clinical Conditions . 2 nd Edition. Churchill Livingstone. Grossman, S. (2013) Porth's Pathophysiology: Concepts of Altered Health States . 9 th Edition. Lippincott. Martini, F.H. et al . (2014) Fundamentals of Anatomy & Physiology . 10 th Edition. Pearson.

Transferrable Skills

Data analysis and interpretation Problem solving Practical skills Application of theory to practice Time management Team-working during group sessions Communication skills Critical analysis Self-directed study

Module Structure

Activity Total Hours
Independent Learning (FT) 155.00
Practicals (FT) 5.00
Assessment (FT) 30.00
Tutorials (FT) 30.00
Lectures (FT) 80.00

Assessment Methods

Component Duration Weighting Threshold Description
Exam (Dept) 01 3.00 70.00 35% Unseen, to assess discipline specific material - exemption 100R
Exam (Dept) 02 1.50 30.00 35% Unseen, to assess special topics exemption 100R