GENERAL & SYSTEMIC PATHOLOGY, PHYSIOLOGY AND MICROBIOLOGY

SHE Level 2
SCQF Credit Points 20.00
ECTS Credit Points 10.00
Module Code M2B521591
Module Leader Edward Ian Pearce
School School of Health and Life Sciences
Subject Vision Sciences
Trimester
  • A (September start)

Summary of Content

This module will provide a grounding in pathological principles and essential disease processes. Commencing at a cellular level, it will build up to the body's response to a variety of factors and introduce systemic disease, with particular reference to disorders that can have ocular manifestation.

Syllabus

Inflammation and Repair Acute inflammation; Chronic inflammation and granulomatous diseases; Wound healing: primary and secondary union complications. The Immunue Response Normal immune system (lymphatic system, thymus, spleen, non-specific immunity); Humoral immunity: actions of immunoglobulins; Cellular immunity; Immunodeficiency; Auto-immune disorders; Hypersensitivity; type I, type II, type III and type IV. Microbiology Distinction between prokaryotic and eukaryotic cells. General features of microorganisms compared to mammalian cells. Specific pathogens (bacteria, viruses, protozoa fungi) will be introduced particularly those that affect the eye. In addition, other agents that cause disease (e.g. prions) will also be introduced. Disorders of Tissue Growth Hyperplasia and hypertrophy; Hypoplasia and atrophy; Metaplasia and dysplasia; Neoplasia: benign and malignanat lesions, metatasis. Cardiovascular Disorders Atheroma; Thrombosis; Embolism; Ischaemia; Infarction; Oedema; Stroke; Transient ischaemic attach; Systemic hypertension. Disorders of the Blood Anaemia; Sickle cell disease; Leucopenia; Haemophilia; Giant cell arteritis; Erythaemia; Thrombocytopenia. Endocrine Disorders Diabetes mellitus; Pituitary disorders; Thyroid disorders. Disorders of Joints and Bones Discorders of skull and skeleton: Rheumatoid arthritis; Osteoarthitis, Juvenile chronic arthritis.

Learning Outcomes

On completion of this module, students should be able to- demonstrate a knowledge and understanding of the principles of pathology and disease processes, from a cellular level to the responses of the body tissues, organs and systems- describe the aetiology, manifestation, treatment and prognosis of a variety of systemic disorders, concentrating on those that affect the eye and/or visual system- apply a knowledge of general pathology and systemic conditions to ocular pathology

Teaching / Learning Strategy

This module will comprise a lecture programme and tutorial/seminar sessions. Peer learning and independent learning is developed when students investigate diseases and syndrome as part of the poster assessment. This will underpin future enquiry skills.

Indicative Reading

Required (one of the following):- 1- Spector TD & Hall P. An Introduction to General Pathology 4/e Churchill Livingstone (2009) 2 - Underwood JCE. General and systemic pathology 5/e Churchill Livingstone (2009) Macfarlane PS. Pathology Illustrated 5/e, Churchill Livingstone (1999) Kanski JJ. Clinical Ophthalmology 6/e. Butterworth Heinemann (2007

Transferrable Skills

Knowledge of a wide variety of systemic diseases that have an impact on the eye and vision. Understanding of the nomenclature used to describe disease and disease processes. Presentation skills appropriate to discuss disease entities with professional peers.

Module Structure

Activity Total Hours
Seminars (FT) 16.00
Independent Learning (FT) 110.00
Lectures (FT) 48.00
Tutorials (FT) 8.00
Assessment (FT) 18.00

Assessment Methods

Component Duration Weighting Threshold Description
Course Work 01 n/a 30.00 35% Pathology Poster and Seminar
Exam (Exams Office) 2.00 70.00 35% unseen written paper