SHE Level 2
SCQF Credit Points 20.00
ECTS Credit Points 10.00
Module Code M2B123705
Module Leader Elaine Gribben
School School of Health and Life Sciences
Subject Biological and Biomedical Sciences
  • B (January start)
  • A (September start)

Pre-Requisite Knowledge

Level 1 Physiology

Summary of Content

This module extends the student's knowledge and understanding of 1. general physiological principles, 2. the physiology and pathophysiology of selected body systems and 3. current approaches to the treatment of important pathological conditions. It also encourages the student to develop a more critical and analytical approach to the interpretation and clinical application of physiological data.


Introductory concepts in pharmacology Cardiovascular system Cardiovascular system in health - physiological control of the heart and blood vessels at the systemic, tissue and cellular levels. Pathophysiology and management of: systemic hypertension, atherosclerosis and coronary heart disease, arrhythmias, congestive heart failure. Respiratory system Principles of, and factors affecting, gas exchange and transport; control of breathing; pulmonary function tests. Respiratory failure - Review of conditions affecting the respiratory system: mismatching of alveolar ventilation to perfusion (chronic bronchitis, bronchial asthma, pulmonary oedema); increase in shunt fraction (adult respiratory distress syndrome, pneumonia); alveolar-capillary block syndrome (pulmonary fibrosis). Renal System Structure and function of the kidneys in health. Diuretics; Pyelonephritis, glomerulonephritis, nephritic and nephritic syndromes, acute renal failure, chronic renal failure. Digestive system Secretion and motility in the alimentary system; digestion and absorption; control mechanisms. Disorders of the alimentary tract - Peptic ulcer; cancer of the stomach; inflammatory bowel disease; malabsorption syndrome; tumours of the small and large intestine. Disorders of liver and pancreas - Review of causes and clinical features of liver disease; liver function tests; pancreatitis; tumours of the pancreas. Nervous system Central nervous system - Brain damage due to direct trauma or cerebral compression; seizure disorders (including pharmacological treatment); cerebral vascular accident (transient ischaemic attack; embolic and thrombotic stroke; motor and sensory consequences); damage to spinal cord (complete and partial transection); multiple sclerosis; degenerative brain disorders (Alzheimer's disease; Creutzfeldt-Jakob's disease; Huntington's disease; Parkinson's disease); pharmacological treatment of degenerative brain disorders. Auditory system Auditory system in health; disorders of auditory function - external, middle and inner ear, central auditory pathways; disorders of vestibular function - vestibular system and reflexes, vertigo, motion sickness, Me9nie8re's disease, diagnostic tests; treatment options .

Learning Outcomes

On successful completion of this module, the student should be able to:1. Demonstrate an advanced knowledge and understanding of the principles of homeostatic mechanisms and the normal functioning and pathophysiology of selected human body systems.2. Discuss the scientific basis of current therapeutic approaches.3. Apply his/her knowledge and understanding in the interpretation, critical analysis and presentation of observed data.4. Apply his/her knowledge in analysing the relationship between normal physiological processes and disease states.5. Relate his/her knowledge of human body systems to modern clinical practice and health care.

Teaching / Learning Strategy

The syllabus will be delivered by distance learning through means of directed reading and student-centred learning assignments. Wherever possible, case-studies will be used to relate theory to clinical findings and therapeutic practice.

Indicative Reading

Grossman. S & Porth, C. M. 9th Ed (2013) Pathophysiology: Concepts of Altered Health States. Lippincott, Williams and Wilkins Additional Recommended Reading Rang, H.P., Dale, M.M. (2015) Pharmacology. 8th edition, Churchill-Livingstone Tortora, G.J., Derrickson, B.H. (2014) Principles of Anatomy & Physiology. 14th edn. John Wiley and Sons.

Transferrable Skills

The students' transferable skills should be extended in the following areas: 1. The analysis, interpretation and presentation of clinical and scientific data. 2. Communication by the written word (via use of extended essays). 3. Time management 4. Independent learning

Module Structure

Activity Total Hours
Independent Learning (FT) 170.00
Assessment (FT) 30.00

Assessment Methods

Component Duration Weighting Threshold Description
Course Work 01 n/a 30.00 35% 2000 word researched essay
Exam (Dept) 02 1.00 25.00 35% MCQ class test
Course Work 03 n/a 10.00 35% workbook 2
Exam (Dept) 01 1.00 25.00 35% MCQ class test
Course Work 02 n/a 10.00 35% workbook 1