SHE Level 2
SCQF Credit Points 20.00
ECTS Credit Points 10.00
Module Code M2B123725
Module Leader Elaine Gribben
School School of Health and Life Sciences
Subject Biological and Biomedical Sciences
  • A (September start)-B (January start)

Pre-Requisite Knowledge

Successful completion of Respiratory Physiology 1

Summary of Content

The module will provide the student with a sound understanding of the pathophysiological changes that occur in a range of respiratory diseases and their effects on lung function. It will explore the aetiology, pathophysiology and pathology of these diseases and also therapeutic intervention utilised. It will expand on the mechanical changes that control ventilation and discuss how these can be assessed. It will also review the use of reference values and expand on their use, calculation and reporting of results and the basic recognition lung condition .


-567 Physiology Respiratory mechanics: anatomy of inspiratory and expiratory muscles, pressure and pressure volume changes during ventilation, airways resistance, work of breathing, dynamic properties of the lungs, static properties of the lungs, physiological determinants of lung volumes, distribution of ventilation and perfusion in the lung. Pathophysiology Diseases and effects on lung function: Intrathoracic airways obstruction (asthma, chronic bronchitis, emphysema); Extrathoracic airways obstruction (fixed, variable); Restrictive ventilatory defects (Pulmonary fibrosis, chest wall diseases, neuromuscular diseases); Hypoxaemia (ventilatory failure, V/Q inequality, anatomical shunts); Hypercapnia (disorders of respiratory centre, respiratory nerves, muscles, chest wall, airways and parenchyma); Pulmonary Embolism Effects of cigarette smoking (chronic bronchitis, emphysema, cancer) Occupational lung disease (pneumoconiosis, asbestosis, farmers lung, asthma, extrinsic allergic Alveolitis) Pharmacology & therapeutics: Steroid trials, nebuliser assessments Physiological measurement Lung function tests: interpretation of the response during a nebuliser or steroid assessment Interpretation of results from spirometry : obstructive & restrictive disease. Interpretation of response to bronchodilator administration. Flow volume curves. Uses and limitations of reference values. Skin prick testing: indications and contraindications for performing skin prick tests, procedure for performing the test, safety precautions, interpretation of results, allergens commonly used, limitation of performing test, other test for allergies (patch testing, RAST test) Interpretation.: Spirometry, Flow volume curves, uses and limitations os reference values, standard residuals, classification of airflow obstruction, full lung function tests (basic recognition), recognition of need to deliver a bronchodilator.

Learning Outcomes

On successful completion of this module, the student should be able to:1. review the pathophysiological changes that occur with common lung diseases. 2. discuss the causes, investigation of and efficacy of the treatment of hyper reactive airways. 3. recognise and interpret basic lung function tests parameters including reversibility studies4. discuss the role of respiratory mechanics in control of breathing5. explain the effects of neuromuscular disease on the respiratory system

Teaching / Learning Strategy

The specialist module material will be delivered mainly by senior NHS Practitioners, clinicians and consultants via a combination of lectures and tutorials together with directed learning exercises, practical problems and data interpretation. Lectures will provide the foundation material for the module which will be supplemented and enhanced by material presented in tutorials and practical sessions. Tutorials will also allow practical applications of individual topics to the students' own work experience to be examined and discussed.

Indicative Reading

Suggested Reading: Cloutier, M. (2007), Respiratory Physiology , Mosby Dakin, J. et al (2003), Making Sense of Lung Function Tests , Arnold Davis, A., Moore, C. (2010), The Respiratory System , 2 nd Edition, Churchill Livingstone Martini, F.H. et al . (2014) Fundamentals of Anatomy & Physiology . 10 th Edition. Pearson. Naish, J. et al . (2011) Medical Sciences . Saunders. Porth, C. M. 9th Edition (2013) Pathophysiology: Concepts of Altered Health States. Lippincott, Williams and Wilkins Rang, H.P. et al . (2015) Rang & Dale's Pharmacology . 8 th Edition. Churchill Livingstone. Tortora, G.J., Derrickson, B.H. (2014), Principles of Anatomy & Physiology. 14th Edition. John Wiley and Sons.

Transferrable Skills

Data analysis and interpretation Problem solving Practical skills Application of theory to practice Time management Teamworking during group sessions Communication skills

Module Structure

Activity Total Hours
Assessment (FT) 20.00
Lectures (FT) 50.00
Independent Learning (FT) 120.00
Tutorials (FT) 10.00

Assessment Methods

Component Duration Weighting Threshold Description
Exam (Dept) 01 1.00 50.00 35% Objective
Exam (Dept) 02 1.00 50.00 35% Short Answer