LUSTRUM Limiting Undetected Sexually Transmitted Infections to Reduce Morbidity (2016-2021)

Around half a million STIs are diagnosed in the UK each year causing significant morbidity and rising health care costs. Sexual health services are under considerable pressure and are failing to meet demand.  Almost 20% of all HIV infections are undiagnosed despite widely available testing. More effective prevention of transmission and detection of undiagnosed HIV would confer considerable health gains.

LUSTRUM aims to improve the sexual health of heterosexual people and men who have sex with men by preventing transmission of STIs and reducing undiagnosed HIV. This five year mixed methods programme unites multidisciplinary experts from eight academic and NHS institutions. The central component is a definitive cluster RCT of APT, a new form of rapid testing and treatment of sex partners of people with chlamydia, UK’s most commonly reported STI.

Researchers: Professor Claudia Estcourt, (Glasgow Caledonian University and Central and North West London NHS Trust), Prof Paul Flowers, Prof David Goldberg, Dr Maria Pothoulaki (Glasgow Caledonian University), Prof Jackie Cassell, Brighton & Sussex Medical School, Mr Merle Symonds Barts Health NHS Trust, Prof Nicola Low University of Bern, Prof Tracy Roberts University of Birmingham,  Dr Rak Nandwani NHS GGC, Dr Andrew Copas, Dr Cath Mercer, Dr Fiona Mapp, Dr Melvina Woode-Owusu, Dame Prof Anne Johnson, Dr John Saunders, Dr Sonali Wayal, Dr Alison Howarth (UCL).

Funder and amount: National Institute for Health Research (NIHR), Programme Grants for Applied Research (RP-PG-0614-20009) £2,49 million