Vascular Biology Group

The Vascular Biology group at Glasgow Caledonian University is a multi-disciplinary group of physiologists, pharmacologists, cell biologists, biochemists and microbiologists, bringing substantive research experience and expertise to investigate an array of issues relating to the fundamental (patho)physiology and cell biology of vascular tissues.

View these short movies that show time lapse microscopy of rat neonatal cardiac myocytes transfected to express the gap junction protein Cx43, tagged with GFP to enable live cell imaging of gap junction plagues.

Key Research interests include:

  • Physiology and pharmacology of smooth muscle
  • Regulation of regional blood flow and vascular resistance in the lung
  • Cellular transport, cell-cell communication and movement of cells within the vasculature and developing atheroma
  • Infections of vascular tissues, including infective endocarditis, the formation of Candida biofilms on medical implants, and compromised host immune response

Since 2001, members of the Vascular Biology group have published over 55 papers in peer reviewed journals and presented their findings at meetings in the UK, Europe and the US. In the last year alone (2004/05), well in excess of half a million pounds in grant income has been raised by members of this grouping, from the Arthritis Research Council, BBSRC, British Heart Foundation, Chief Scientists’Office, Diabetes UK, the Royal Society and Tenovus Scotland, involving dynamic collaborations with colleagues in national and international institutions.

The group hosts visiting speakers, meets regularly to discuss research, meetings and grant opportunities, and has active postgraduate and postdoctoral involvement.

Members:

Douglas Bovell

Ann Graham

Sue Lang

Allan MacDonald

Patricia Martin

Jane Nally

Angus Shaw