Professor Alan Tomlinson

Research Professor (P/T), Registered Optometrist

ROOM: A109
T: +44 141 331 3380
F: +44 (0)141 331 3387
E: A.Tomlinson@gcal.ac.uk

Alan Tomlinson qualified as an optometrist in the United Kingdom (University of Bradford) and obtained a PhD from the University of Manchester. In 1999 he was awarded a DSc by UMIST for contributions to research in contact lenses and anterior ocular surface physiology. He has held academic appointments as Lecturer at UMIST and Professor of Optometry at Indiana University and the Southern California College of Optometry, USA. In addition he has been a Clinical Research Director for a US pharmaceutical company. Alan Tomlinson has been Professor and Head of the Glasgow Caledonian University, since 1992 and is the Director of the new Centre for Vision in Health at Glasgow Caledonian University.

Professor Tomlinson is the author of over 100 research papers in refereed journals. He has published extensively on contact lenses and anterior ocular surface physiology. In recent years mostly on the pathophysiology of dry eye and the pathogenesis of corneal infections associated with contact lens wear. He has contributed chapters to several text books and is the author of the text book "Complications of Contact Lens Wear" published by Mosby.

Recent Publications

Oliver, K.M., O'Brart, D.P., Stephenson, C.G., Hemenger, R.P., Applegate, R.A., Tomlinson, A., & Marshall, J. (2001). Anterior corneal optical aberrations induced by photorefractive keratectomy for hyperopia. J Refract Surg, 17 (4), 406-413.

Tomlinson, A., Blades, K.J., & Pearce, E.I. (2001). What does the phenol red thread test actually measure? Optom Vis Sci, 78 (3), 142-146.

Tomlinson, A., Pearce, E.I., Simmons, P.A., & Blades, K. (2001). Effect of oral contraceptives on tear physiology. Ophthalmic Physiol Opt, 21 (1), 9-16.

Beattie, T.K., Tomlinson, A., & Seal, D.V. (2002). Anti-Acanthamoeba efficacy in contact lens disinfecting systems. British Journal of Ophthalmology, 86 (11), 1319-1320.

Craig, J.P., Tomlinson, A., Patterson, N.S., Reid, V.E., & McFadyen, A.K. (2002). Tear production measurement, basal or reflex assessment? Adv Exp Med Biol, 506 (Pt B), 1159-1163.

Craig, J.P., Tomlinson, A., Patterson, N.S., Reid, V.E.H., & McFadyen, A.K. (2002). Tear production measurement, basal or reflex assessment? In: Lacrimal Gland, Tear Film, and Dry Eye Syndromes 3: Basic Science and Clinical Relevance, Pts a & B, 506 (pp. 1159-1163). New York: Kluwer Academic/Plenum Publ.

Pearce, E.I., Tomlinson, A., Blades, K.J., Falkenberg, H.K., Lindsay, B., & Wilson, C.G. (2002). Effect of an oil and water emulsion on tear evaporation rate. Adv Exp Med Biol, 506 (Pt A), 419-423.

Thai, L.C., Tomlinson, A., & Ridder, W.H. (2002). Contact lens drying and visual performance: the vision cycle with contact lenses. Optom Vis Sci, 79 (6), 381-388.

Thai, L.C., Tomlinson, A., & Simmons, P.A. (2002). In vitro and in vivo effects of a lubricant in a contact lens solution. Ophthalmic Physiol Opt, 22 (4), 319-329.

Tomlinson, A., Thai, L.C., Doane, M.G., & McFadyen, A. (2002). Reliability of measurements of tear physiology. Adv Exp Med Biol, 506 (Pt B), 1097-1105.

Tomlinson, A., Thai, L.C., Doane, M.G., & McFadyen, A. (2002). Reliability of measurements of tear physiology. In: Lacrimal Gland, Tear Film, and Dry Eye Syndromes 3: Basic Science and Clinical Relevance, Pts a & B, 506 (pp. 1097-1105). New York: Kluwer Academic/Plenum Publ.

Beattie, T.K., Seal, D.V., Tomlinson, A., McFadyen, A.K., & Grimason, A.M. (2003). Determination of amoebicidal activities of multipurpose contact lens solutions by using a most probable number enumeration technique. J Clin Microbiol, 41 (7), 2992-3000.

Beattie, T.K., Tomlinson, A., McFadyen, A.K., Seal, D.V., & Grimason, A.M. (2003). Enhanced attachment of acanthamoeba to extended-wear silicone hydrogel contact lenses: a new risk factor for infection? Ophthalmology, 110 (4), 765-771.

Beattie, T.K., Tomlinson, A., & Seal, D.V. (2003). Surface treatment or material characteristic: the reason for the high level of Acanthamoeba attachment to silicone hydrogel contact lenses. Eye Contact Lens, 29 (1 Suppl), S40-43; discussion S57-49, S192-194.

Ridder, W.H., & Tomlinson, A. (2003). The effect of artificial tears on visual performance in normal subjects wearing contact lenses. Optometry and Vision Science, 80 (12), 826-831.

Seal, D.V., Beattie, T.K., Tomlinson, A., Fan, D., & Wong, E. (2003). Acanthamoeba keratitis. British Journal of Ophthalmology, 87 (4), 516-517.

Booton, G.C., Rogerson, A., Bonilla, T.D., Seal, D.V., Kelly, D.J., Beattie, T.K., Tomlinson, A., Lares-Villa, F., Fuerst, P.A., & Byers, T.J. (2004). Molecular and physiological evaluation of subtropical environmental isolates of Acanthamoeba spp., causal agent of Acanthamoeba keratitis. Journal of Eukaryotic Microbiology, 51 (2), 192-200.

Thai, L.C., Tomlinson, A., & Doane, M.G. (2004). Effect of contact lens materials on tear physiology. Optom Vis Sci, 81 (3), 194-204.

Tomlinson, A., & Khanal, S. (2005). Assessment of tear film dynamics: quantification approach. Ocul Surf, 3 (2), 81-95.

Beattie, T.K., Tomlinson, A., & McFadyen, A.K. (2006). Attachment of Acanthamoeba to first- and second-generation silicone hydrogel contact lenses. Ophthalmology, 113 (1), 117-125.

Tomlinson, A., Khanal, S., Ramaesh, K., Diaper, C., & McFadyen, A. (2006). Tear film osmolarity: determination of a referent for dry eye diagnosis. Invest Ophthalmol Vis Sci, 47 (10), 4309-4315.

Khanal, S., Tomlinson, A., Pearce, E.I., & Simmons, P.A. (2007). Effect of an oil-in-water emulsion on the tear physiology of patients with mild to moderate dry eye. Cornea, 26 (2), 175-181.

Tomlinson, A. (2007). Ocular surface research at glasgow caledonian university, Scotland. Ocul Surf, 5 (1), 62-64.

Recent Invited Lecture Presentations

‘Objective and Subjective Measurements of Ocular Dryness.’

Presentation at British Congress of Optometry and Vision Science, Glasgow, Sept 1999.

‘20th Century Vision: The Contact Lens Adventure.’

Max Schapero Memorial Lecture, American Academy of Optometry, Seattle, WA, USA - Dec 1999.

‘Reliability of Measurements of Tear Physiology.’

Presentation at the Tear Film and Ocular Surface Society, Maui, Hawaii, USA – Nov 2000.

‘Vision with Contact Lenses – Everything Changes with Time.’

Presentation at BCLA Meeting, Brighton, June 2001.

‘Tear Film Abuse : The Effects of Contact Lens Wear on the Tear Film.’

Presentations at the Swedish Optometric Association, Stockholm, Sweden – March 2002

Acanthamoebal Keratitis in the Age of Silicone Hydrogels

Presentation at Nissel Memorial Lecture, BCLA, London – November 2002

‘Effect of Artificial Tears on Visual Performance with Contact Lenses’

Presentation at the American Academy of Optometry, San Diego, USA – Dec 2002

Objective Measurements of Tear Physiology

Presentation at AAO/ARVO Research Symposium, Dallas, USA – December 2003

Grants

Recent External Grant Income

£28,012 ($40,338) - Cyclosporine Emulsion Vehicle – Effects on Tear Evaporation Rate – Allergan 2000.

£26,340 ($36,816) - Effects of Ocular Lubricants on the Pre-Contact Lens Tear Film – Allergan 2001.

£54,560- Testing of New Preparation of Povidone Iodine for Ophthalmic Use- Renaissance Healthcare 2002.

£32,000 ($50,000) - Study of Chronic Application of an Oil Water Emulsion on Tear Physiology – Allergan 2003

£48,000 - Study of a Lipomimetic Eyedrop on Tear Physiology – Pfizer 2003

£64,700 - Novel Dry Eye Therapy, Sequani Ltd 2003

£31,000 - Study of Chronic Use of Emulsion Eye Drop, Allergan 2003

£8,500 - Extension to Povidone Iodine Study – Renaissance Healthcare 2004

£8,500 - Development of a Stress Test for Dry Eye.  Sequani, 2005

£18,840 - Effect of Artificial Tear Supplements in the Relief of Environmental Dry Eye - Allergan, 2005

£56,400 - Efficacy of Artificial Tears in Management of Dry Eye- SIFI, 2007