Research Group Leader
Professor Ann Graham
Tel: +44(0)141 331 3722
Professor Graham is interested in the diverse mechanisms by which obesity can act as a ‘driver’ for many of the co-morbidities associated with Type 2 Diabetes Mellitus, and has been principal investigator on a number of projects funded by Diabetes UK examining dysregulated cellular lipoprotein metabolism. She has published extensively in the area of vascular research, and lipid metabolism, has led research groups in industry and academia and gained grant funding from the BBSRC, British Heart Foundation, British Skin Foundation, the Leverhulme Trust and Heart Research UK.
The Diabetes Research Group (DRG) brings together individual researchers and their research groups, so that their conjoined expertise may be most effectively used to avert the impact of the obesity ‘epidemic’ responsible for the rise in Type 2 Diabetes Mellitus (T2D) in both industrialised and developing societies. Our biological expertise in this area, supported by major funding agencies, include islet transplantation, adipokine and lipid biology, cell-to-cell communication, with developing interests in antioxidant function, bacterial infection, retinopathy and inflammatory pain.
Our aim is to increase the impact of basic scientific research by applying the knowledge gained within a translational framework to improve the care for patients with T2D and associated co-morbidities. Equally, we are developing multidisciplinary, multi-component studies, incorporating psychological, nutritional and physical activity approaches, underpinned by modern, cutting-edge genetic and biochemical techniques, to inform how treatment regimens may be optimized.